ABSTRACT
Many mucocutaneous lesions of the oral cavity have similar clinical features and therefore the histpathologic findings are very important in correct diagnosis and differential diagnosis of each lesion. The aim of this study was to assess the agreement between clinical and histopathologic diagnoses in mucocutaneous lesions of the oral cavity during 30 years [1979-2009] in Mashhad dental School. In this retrospective study, a total of 334 patients with mucocutaneus lesions were analyzed in Mashhad dental school from1979 to 2009. Patient's data including age, gender, location, clinical diagnosis and histopathologic diagnosis were recorded. Data were analyzed through SPSS 11.5 Software. In this study, there was an agreement between clinical and histopathologic diagnoses in 295 subjects [77.5%] with oral mucocutaneus lesions. All subjects with pemphigoid and white spongy nevus showed total agreement between clinical and histopathologic diagnoses. Atrophic and pigmenteted lichen planus also showed the highest percentage of agreement in lichen planus groups. In mucocutaneous lesions, clinical, radiographic, and histopathologic findings are necessary for definitive diagnosis of mucocutaneous lesions